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Antiepileptics in Serum / Plasma with UHPLC 质谱方案

2025-04-27

Antiepileptics with UHPLC
This ClinRep® UHPLC Complete Kit shows an identical analyte spectrum as the ClinRep® HPLC Complete Kit with order no. 14000. Thus, the following 16 substances can be quantified simultaneously: carbamazepine, eslicarbazepine, ethosuximide, felbamate, lacosamide, lamotrigine, oxcarbazepine, phenobarbital, phenytoin, primidone, rufinamide, sulthiame and zonisamide as well as the pharmacologically active metabolites N-desmethylmethsuximide, 10-hydroxycarbamazepine and carbamazepine epoxide. The chromatographic separation is performed with an injection interval of 5 min only.

This ClinRep® UHPLC Complete Kit shows an identical analyte spectrum as the ClinRep® HPLC Complete Kit with order no. 14000. Thus, the following 16 substances can be quantified simultaneously: carbamazepine, eslicarbazepine, ethosuximide, felbamate, lacosamide, lamotrigine, oxcarbazepine, phenobarbital, phenytoin, primidone, rufinamide, sulthiame and zonisamide as well as the pharmacologically active metabolites N-desmethylmethsuximide, 10-hydroxy-carbamazepine and carbamazepine epoxide. The chromatographic separation is performed with an injection interval of 5 min only.
Sample Preparation


Chromatography


Ordering Information

Order No. Description Quantity
BYRI-14100 ClinRep® Complete Kit for Antiepileptics 1 pce.
  in Serum / Plasma by UHPLC  
  for 100 assays  
  Contents:  
  Mobile Phase A 1 x 14108
  Mobile Phase B 1 x 14109
  Standard Solution Antiepileptics 3 1 x 14011
  Standard Solution Antiepileptics 4 1 x 14111
  Precipitant P with Internal Standard 1 x 14012
  Serum Calibrator Antiepileptics 3, lyophil. 1 x 14013
  Sample Preparation Vials 1 x 14020
  Diluting Solution D 1 x 14021
  Separately available components:  
BYRI-14108 Mobile Phase A 400 ml
BYRI-14109 Mobile Phase B 200 ml
BYRI-14011 Standard Solution Antiepileptics 3 3 ml
BYRI-14111 Standard Solution Antiepileptics 4 3 ml
BYRI-14012 Precipitant P with Internal Standard 20 ml
BYRI-14013 Serum Calibrator Antiepileptics 3, lyophil. 3 ml
BYRI-14113 Serum Calibrator Antiepileptics 4, lyophil. 3 ml
BYRI-14020 Sample Preparation Vials 100 pcs.
BYRI-14021 Diluting Solution D 25 ml
  Start Accessory:  
BYRI-14130 Analytical Column with test chromatogram 1 pce.
  ClinChek® Controls:  
BYRI-14082 Serum Control Antiepileptics 3, lyophil.Level I, II 2 x 5 x 3 ml
BYRI-14182 Serum Control Antiepileptics 4, lyophil.Level I, II 2 x 5 x 3 ml

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